Preparation and Properties of Biodegradable Polyurethane Scaffolds for Tissue Engineering

Xian Yun He; Yong Jun Xu; Ying Jun Wang; Gang Wu; Bo Yuan

doi:10.4028/www.scientific.net/AMM.513-517.95

Paper Titles

Simple Preparation of Well-Dispersed Nanosized α-Fe₂O₃
p.78

The Preparation and Characterization of the Mesoporous Poly(bisphenol-A carbonate) – Silica Nanocomposites
p.82

Synthesis and Characterization of an Amphiphilic Nanoparticles Based on Chitosan Oligosaccharide-Grafted-Polycaprolactone
p.86

Finite Element Analysis of the Vibration Characteristics of Castellated Composite Beams
p.91

Preparation and Properties of Biodegradable Polyurethane Scaffolds for Tissue Engineering
p.95

Production Parameters Optimization of Polyacrylonitrile Precursor Fiber
p.100

Testing Study on Rock-Like Materials under Water Pressure Conditions
p.104

Research on the Preparation of Economical Powder Concrete-UHPC
p.108

The Study on Young's Modulus of Multilayered Cu/Ni Multilayered Nano Thin Films by Molecular Dynamics Simulation
p.113

HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 513-517Preparation and Properties of Biodegradable...

Preparation and Properties of Biodegradable Polyurethane Scaffolds for Tissue Engineering

Abstract:

3D porous scaffolds were produced by a combined salt leaching-phase inverse technique. Results showed that micorpores and macropores distributed in the produced scaffolds with high porosity (more than 75%). The interconnectivity can be influenced by the use of methanol and water as a nonsolvent to induce liquidliquid phase separation. The addition of the nonsolvent and NaCl had influence on compression property of the scaffolds.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Applied Mechanics and Materials (Volumes 513-517)

Pages:

95-99

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.513-517.95

Citation:

Cite this paper

Online since:

February 2014

Authors:

Xian Yun He*, Yong Jun Xu, Ying Jun Wang, Gang Wu, Bo Yuan

Keywords:

Biodegradable Polyurethane Scaffolds, Preparation, Salt Leaching-Phase Inverse Technique, Tissue Engineering

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] Gorna, K., and Gogolewski, S. Biodegradable porous polyurethane scaffolds for tissue repair and regeneration, Journal of Biomedical Materials Research Part A, 2006, 79A, 128-138.

DOI: 10.1002/jbm.a.30708

Google Scholar

[2] Heijkants, R. G. J. C., van Calck, R. V., van Tienen, T. G., de Groot, J. H., Pennings, A. J., Buma, P., Veth, R. P. H., and Schouten, A. J. Polyurethane scaffold formation via a combination of salt leaching and thermally induced phase separation, Journal of Biomedical Materials Research Part A, 2008, 87A, 921-932.

DOI: 10.1002/jbm.a.31829

Google Scholar

[3] Xianyun He, Z. Z., Yingjun Wang, Gang Wu, Zhiwen Zheng, Qunfang Wang, Yang Liu. (2012) New method for coupling collagen on biodegradable polyurethane for biomedical application, journal of Applied Polymer Science, 2012, vol. 126, E353-E360.

DOI: 10.1002/app.36742

Google Scholar

[4] Zhang, R., and Ma, P. X. Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology, Journal of Biomedical Materials Research 1999, 44, 446-455.

DOI: 10.1002/(sici)1097-4636(19990315)44:4<446::aid-jbm11>3.0.co;2-f

Google Scholar

[5] Shao, X. X., Hutmacher, D. W., Ho, S. T., Goh, J. C. H., and Lee, E. H. Evaluation of a hybrid scaffold/cell construct in repair of high-load-bearing osteochondral defects in rabbits, Biomaterials, 2006, 27, 1071-1080.

DOI: 10.1016/j.biomaterials.2005.07.040

Google Scholar

[6] De Groot, J. H., Nijenhuis, A. J., Bruin, P., Pennings, A. J., Veth, R. P. H., Klompmaker, J., and Jansen, H. W. B. Use of porous biodegradable polymer implants in meniscus reconstruction. 1) Preparation of porous biodegradable polyurethanes for the reconstruction of meniscus lesions, Colloid and Polymer Science, 1990, 268, 1073-1081.

DOI: 10.1007/bf01410672

Google Scholar

[7] Walheim, S., Ramstein, M., and Steiner, U. Morphologies in ternary polymer blends after spin-coating, Langmuir, 1999, 15, 4828-4836.

DOI: 10.1021/la981467e

Google Scholar