Progress on OCPs and Chronic Disease

Article Preview

Abstract:

The organochlorine pesticides (OCPs) including a large group of insecticides were widely used in the world in the agriculture and household. OCPs are organic compounds that are resistant to environmental degradation, bioaccumulated in body, and enlarged in the food chain, they are great harm to humans and animals. Although OCPs have been banned for about 40 years, they are still remained in the environment. OCPs are toxic to human and animals, and some compounds have been identified as carcinogenic, mutagenic, and teratogenic. OCPs are also considered as endocrine disruptors, which interfere with the hormone system and can cause birth defects, reproductive and developmental disorders, as well as some cancerous tumors. There is ongoing concern over the risks to human and wildlife reproductive health of OCPs. This overview introduces the effects of OCPs on human reproduction.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

383-387

Citation:

Online since:

February 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] J. Gao, H. Zhou, G. Pan, Factors Influencing the Persistence of Organochlorine Pesticides in Surface Soil from the Region around the Hongze Lake, China, Science of The Total Environment. 443(2013)7-13.

DOI: 10.1016/j.scitotenv.2012.10.086

Google Scholar

[2] T.C. Medehouenou, P. Ayotte, P.H. Carmichael, Polychlorinated biphenyls and organochlorine pesticides in plasma of older Canadians, Environmental Research. 111(2011)1313-1320.

DOI: 10.1016/j.envres.2011.09.017

Google Scholar

[3] F. Pan, L.L. Wang, H. Zhao, Lindane production of a corporate relocation legacy venues HCH Residues in soil characteristics, Environmental Science. 78(2013)705-711.

Google Scholar

[4] P. Jakszyn, F. Goñi, A. Etxeandia, Serum levels of organochlorine pesticides in healthy adults from five regions of Spain, Chemosphere. 76(2009)1518-1524.

DOI: 10.1016/j.chemosphere.2009.05.048

Google Scholar

[5] Y.L. Wang, Y.J. Cai, Stockholm Convention on Persistent Organic Pollutants to add some research progress, Chinese Science: Chemistry. 67(2012)99-123.

Google Scholar

[6] Mostafalou, S.M. Abdollahi, Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives, Toxicology and Applied Pharmacology. 268(2013)157-177.

DOI: 10.1016/j.taap.2013.01.025

Google Scholar

[7] J. Liu, M. Zhao, S. Zhuang, Y. Yang, Low concentrations of o, p'-DDT inhibit gene expression and prostaglandin synthesis by estrogen receptor-independent mechanism in rat ovarian cells, Plos One. 7(2012)49-56.

DOI: 10.1371/journal.pone.0049916

Google Scholar

[8] M. Porta, T. Lopez, M. Gasull, Distribution of blood concentrations of persistent organic pollutants in a representative sample of the population of Barcelona in 2006, and comparison with levels in 2002, Science Total Environmental. 423(2012).

DOI: 10.1016/j.scitotenv.2012.02.001

Google Scholar

[9] N. Wang, L. Shi, D. Kong, Accumulation levels and characteristics of some pesticides in human adiposetissue samples from southeast China, Chemosphere. 84(2011)964–971.

DOI: 10.1016/j.chemosphere.2011.05.062

Google Scholar

[10] J. Wang, H.Y. Song, P.J. Zhang, Reproductive toxicity of pesticides Review, Pesticides. 11(2005)12-13.

Google Scholar

[11] M.P. Longnecker, Invited commentary: Why DDT matters now, Am J Epidemiol. 162(2005) 726-728.

DOI: 10.1093/aje/kwi277

Google Scholar

[12] I. Gerhard, V. Daniel, S. Link, Chlorinated hydrocarbons in women with repeated miscarriages, Environ HealthPerspect. 106(1998)675–681.

DOI: 10.1289/ehp.98106675

Google Scholar

[13] D.C.G. Law, M.A. Klebanoff, J.W. Brock, Maternal serum levels of polychlorinated Biphenyls and 1, 1-dichloro-2, 2-bis(p-chlorophenyl)ethylene (DDE) and time to pregnancy, Am J Epidemiol. 162(2005)523–532.

DOI: 10.1093/aje/kwi240

Google Scholar

[14] S.A. Martin, S.D. Harlow, F. Sowers, DDT metabolite and androgens in African-Americanfarmers, Epidemiology. 13(2002)454–458.

DOI: 10.1097/00001648-200207000-00014

Google Scholar

[15] M.A. Dalvie, J.E. Myers, M.L. Thompson, The long-term effects of DDT exposure on semen, fertility, and sexual function of malaria vector-control workers in Limpopo Province, South Africa, Environmental Resreach. 96(2004)1–8.

DOI: 10.1016/j.envres.2003.09.002

Google Scholar

[16] N.H. Aneck-Hahn, G.W. Schulenburg, M.S. Bornman, Impaired semen quality associated with environmental DDT exposure in young men living in a malaria area in the Limpopo Province, South Africa, Journal of Andrology. 28(2007)423-434.

DOI: 10.2164/jandrol.106.001701

Google Scholar

[17] B.M. Messaros, M.G. Rossano, G. Liu, Negative effects of serum p, p'-DDE on sperm parameters and modification by genetic polymorphisms, Environmental Research. 109(2009)457-464.

DOI: 10.1016/j.envres.2009.02.009

Google Scholar

[18] M. Sara, A. Mohammad, Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives, Toxicology and Applied Pharmacology. 268(2013)157-177.

DOI: 10.1016/j.taap.2013.01.025

Google Scholar

[19] K. Mishra, R.C. Sharma, Assessment of organochlorine pesticides in human milk and risk exposure to infants from North-East India, Science of The Total Environment. 409(2011) 4939-4949.

DOI: 10.1016/j.scitotenv.2011.07.038

Google Scholar

[20] W.Y. Qu, R.P. Suri, X.H. Bi, Exposure of young mothers and newborns to organochlorine pesticides (OCPs) in Guangzhou, China, Science of The Total Environment. 408(2010)3133-3138.

DOI: 10.1016/j.scitotenv.2010.04.023

Google Scholar

[21] M. Weselak, T.E. Arbuckle, W. Foster, Pesticide exposures and developmental outcomes: the epidemiological evidence, Toxicol. Environ. Health B Crit. Rev. 10 (2007)41 -80.

DOI: 10.1080/10937400601034571

Google Scholar

[22] C.M. Rocheleau, P.A. Romitti, L.K. Dennis, Pesticides and hypospadias: a meta-analysis, Pediatr. Urol. 5(2009)17–24.

Google Scholar

[23] A.D. Ngo, R. Taylor, C.L. Roberts, Association between Agent Orange and birth defects: systematic review and meta-analysis, Intel Epidemiol. 35(2006)1220 –1230.

DOI: 10.1093/ije/dyl038

Google Scholar

[24] M.F. Cavieres, Pesticide exposure and reproductive and birth defects. Critical anal-ysis of epidemiological and experimental evidence, Rev. Med. Chil. 132 (2004)873–879.

Google Scholar

[25] P. Dewan, V. Jain, P. Gupta. Organochlorine pesticide residues in maternal blood, cord blood, placenta, and breastmilk and their relation to birth size, Chemosphere. 90(2013)1704-1710.

DOI: 10.1016/j.chemosphere.2012.09.083

Google Scholar

[26] E. Sharma, M. Mustafa, R. Pathak, A case control study of gene environmental interaction in fetal growth restriction with special reference to organochlorine pesticides, European Journal of Obstetrics & Gynecology and Reproductive Biology. 161(2012).

DOI: 10.1016/j.ejogrb.2012.01.008

Google Scholar

[27] B.A. Cohn, P.M. Cirillo, M. Wolff, DDT and DDE exposure in mothers and time to pregnancy in daughter, Lancet. 361(2003)2205–2206.

DOI: 10.1016/s0140-6736(03)13776-2

Google Scholar

[28] F.H. Pierik, A. Burdorf, J.A. Deddens, Maternal and paternal risk factors for cryptorchidism and hypospadias: Acase-control study in newborn boys, Environmental Health Perspect. 112(2004)1570–1576.

DOI: 10.1289/ehp.7243

Google Scholar