Viscoelastic Properties of Phagocytes in Arteriosclerotic Origin

Abstract:

A micropipette aspiration technique was adopted to investigate the viscoelastic properties of phagocytes of arteriosclerotic origin. A standard linear solid model was employed to fit the experimental data and three viscoelastic coefficients were used to compare the mechanical properties of the phagocytes in different phases during arteriosclerostic development. The experimental results indicated that prior to the formation of arteriosclerosis, the mobility and deformability of the marcopahges matured from monocytes decreased, and their rigidity increased. At the initial stage of arteriosclerosis formation, the mobility and deformability of the foam-cells further decreased. This finding may have important implication in the research field of arteriosclerosis.

• Periodical: Applied Mechanics and Materials (Volume 540)
• Pages: 321-325
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.540.321
• Online since: April 2014
• Authors: Wei Zeng*, Yan Rong Shi, Xiao Yan Deng
• Keywords: Arteriosclerosis, Micropipette Aspiration, Phagocyte, Viscoelasticity

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