Investigation into the Existence of Cavitation within Haemodialysis Needles

Article Preview

Abstract:

The source of micro bubbles within the haemodialysis extracorporeal circuit is currently unknown. If micro bubbles enter the body they may result in several health issues. Micro bubbles may be formed near the needles if the local pressure drops below the vapour pressure of blood, causing cavitation. Cavitation has been hypothesised to occur at the arterial needle due to the lower local pressures from the suction forces created by the peristaltic blood pump. A CFD model was developed to study the possible inception of cavitation from various options. Variations in needle flow rate and needle orientation were studied using a transient waveform, to determine the clinical conditions in which cavitation might occur. Cavitation may occur within the needle bore when the flow rates are temporarily elevated in the waveform. Needle orientation was also found to have no effect on cavitation potential.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

199-204

Citation:

Online since:

May 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] Stegmayr, B., Forsberg, U., Jonsson, P. and Stegmayr, C., The sensor in the venous chamber does not prevent passage of air bubbles during hemodialysis. Artificial Organs, 2007. 31(2): pp.162-6.

DOI: 10.1111/j.1525-1594.2007.00358.x

Google Scholar

[2] Rollé, Florence, Pengloan, Josette, Abazza, Mohamed, Halimi, Jean Michel, Laskar, Michel, Pourcelot, Léandre and Tranquart, François, Identification of microemboli during haemodialysis using Doppler ultrasound. Nephrology Dialysis Transplantation, 2000. 15(9): pp.1420-1424.

DOI: 10.1093/ndt/15.9.1420

Google Scholar

[3] Jonsson, Per, Karlsson, Lars, Forsberg, Ulf, Gref, Margareta, Stegmayr, Christofer and Stegmayr, Bernd, Air Bubbles Pass the Security System of the Dialysis Device Without Alarming. Artificial Organs, 2007. 31(2): pp.132-139.

DOI: 10.1111/j.1525-1594.2007.00352.x

Google Scholar

[4] Stegmayr, Christofer J., Jonsson, Per, Forsberg, Ulf and Stegmayr, Bernd G., Development of Air Micro Bubbles in the Venous Outlet Line: An In Vitro Analysis of Various Air Traps Used for Hemodialysis. Artificial Organs, 2007. 31(6): pp.483-488.

DOI: 10.1111/j.1525-1594.2007.00411.x

Google Scholar

[5] Forsberg, Ulf, Jonsson, Per, Stegmayr, Christofer and Stegmayr, Bernd, Microemboli, developed during haemodialysis, pass the lung barrier and may cause ischaemic lesions in organs such as the brain. Nephrology Dialysis Transplantation, 2010. 25(8): pp.2691-2695.

DOI: 10.1093/ndt/gfq116

Google Scholar

[6] Woltmann, D., Fatica, R. A., Rubin, J. M. and Weitzel, W., Ultrasound detection of microembolic signals in hemodialysis accesses. American Journal of Kidney Disease, 2000. 35(3): pp.526-8.

DOI: 10.1016/s0272-6386(00)70207-1

Google Scholar

[7] Graves, Glenda D, Arterial and Venous Pressure Monitoring During Haemodialysis. Nephrology Nursing Journal, 2001. 28(1): pp.23-30.

Google Scholar

[8] Chambers, Sean D, Bartlett, Robert H and Ceccio, Steven L, Determination of the in vivo cavitation nuclei characteristics of blood. American Society for Artificial Internal Organs, 1999. 45(6): pp.541-549.

DOI: 10.1097/00002480-199911000-00007

Google Scholar

[9] Lin, Hsin-Yi, Bianccucci, Brian A., Deutsch, Steven, Fontaine, Arnold A. and Tarbell, J. M., Observation and Quantification of Gas Bubble Formation on a Mechanical Heart Valve. J Biomech Eng, 2000. 122(4): pp.304-309.

DOI: 10.1115/1.1287171

Google Scholar

[10] Grollman, A., The Vapour Pressure of dog's Blood at Body Temperature. Journal of General Physiology, 1928. 11(5): pp.495-506.

Google Scholar

[11] Fairshter, R. D., Vaziri, N. D. and Mirahmadi, M. K., Lung pathology in chronic hemodialysis patients. Artificial Organs, 1982. 5(2): pp.97-100.

Google Scholar

[12] Barak, Michal and Katz, Yeshayahu, Microbubbles*: Pathophysiology and Clinical Implications. Chest, 2005. 128(4): pp.2918-32.

Google Scholar

[13] Sharp, M. Keith and Mohammad, S. Fazal, Scaling of Hemolysis in Needles and Catheters. Annals of Biomedical Engineering, 1998. 26(5): pp.788-797.

DOI: 10.1114/1.65

Google Scholar

[14] Schlicher, Robyn K., Hutcheson, Joshua D., Radhakrishna, Harish, Apkarian, Robert P. and Prausnitz, Mark R., Changes in Cell Morphology Due to Plasma Membrane Wounding by Acoustic Cavitation. Ultrasound in Medicine & Biology, 2010. 36(4): pp.677-692.

DOI: 10.1016/j.ultrasmedbio.2010.01.010

Google Scholar

[15] Sundaram, Jagannathan, Mellein, Berlyn R. and Mitragotri, Samir, An Experimental and Theoretical Analysis of Ultrasound-Induced Permeabilization of Cell Membranes. Biophysical Journal, 2003. 84(5): pp.3087-3101.

DOI: 10.1016/s0006-3495(03)70034-4

Google Scholar

[16] Konner, k., A primer on the av fistula—Achilles' heel, but also Cinderella of haemodialysis. Nephrology Dialysis Transplantation, 1999. 14(9): p.2094-(2098).

DOI: 10.1093/ndt/14.9.2094

Google Scholar

[17] Batchelor, G K, An Introduction to Fluid Dynamics. 2002, Cambridge, United Kingdom: Press Syndicate of the University of Cambridge. 615.

Google Scholar