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Effects of Graphene Oxide on the Structure of Human γ-Globulins

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Abstract:

Graphene and its derivatives have become great concern in biomedical fields. Though many investigations about their toxicity have been reported, investigation on the interaction with γ-globulins is lacking. In this work, we studied the effects of the graphene oxide (GO) on the structure of γ-globulins by UV absorption spectra, circular dichroism (CD) and fuorescence spectra. The results showed that GO could alter the secondary structures and conformation. The results obtained in this study provided good insight into understanding the biomedical application of GO in vivo.

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Info:

Periodical:

Applied Mechanics and Materials (Volumes 556-562)

Pages:

47-50

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.556-562.47

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Online since:

May 2014

Authors:

Ru Feng, Yan Peng Jiao*, Chang Ren Zhou

Keywords:

Graphene Oxide, Structure, γ-Globulins

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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