A New Technique to Reconstruct CAP Using Dual-Channel Peripheral Pressure Singal Based on Blind Identification

Abstract:

Central aortic pressure (CAP) is pathophysiologically more relevant than peripheral pressures for the evaluation of cardiovascular disease. However, the invasive measurement of CAP is restricted in the clinical. In this study, we proposed a new technique to reconstruct CAP using dual-channel peripheral pressure signal based on blind identification. First, we establish a single input multi-output (SIMO) physics-based model, the common model input then can be estimated directly using input subspace (LS) method. In order to demonstrate the feasibility of this technique, we use two interventional surgery patients conducting human trials, in which non-invasive radial and finger blood pressure (BP) waveform as well as reference invasive CAP are recorded simultaneously. The estimated CAP is very closer in morphology to its measured (selected 30s segments, the root mean square errors is 2.02mmHg). In conclusion, noting that dual-peripheral pressure measurements are all non-invasive, it is conducive to the clinical promotion and application.

• Periodical: Applied Mechanics and Materials (Volumes 602-605)
• Pages: 2253-2256
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.602-605.2253
• Online since: August 2014
• Authors: Xiao Ping Yang*, Chao Ma, Xue Cong Wu
• Keywords: Blind Identification, LS Method, SiMo

References

[1] Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens. 2003; 21: 1011–1053.

DOI: 10.1097/00004872-200306000-00001

[2] Williams B, Lacy P S, Thom S M. Differential impact of blood pressure — lowering drugs on central aortic-pressure and clinical outcomes principal results of the conduit artery function evaluation (CAFE) study. Circulation, 2006, 113: 1213–1225.

DOI: 10.1161/circulationaha.105.595496

[3] M. Karamanoglu, M. O'ROURKE. An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man., European heart journal 1993; 14: 160-167.

DOI: 10.1093/eurheartj/14.2.160

[4] C.H. Chen, E. Nevo. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure: validation of generalized transfer function., Circulation 1997; 95: 1827-1836.

DOI: 10.1161/01.cir.95.7.1827

[5] N. Westerhof, Forward and backward waves in the arterial system, Cardiovascular Research, vol. 6, pp.648-656, (1972).

DOI: 10.1093/cvr/6.6.648

[6] N. Stergiopulos, Physical basis of pressure transfer from periphery to aorta: a model-based study, American Journal of Physiology-Heart and Circulatory Physiology, vol. 274, no. 4, pp. H1386-H1392, (1998).

DOI: 10.1152/ajpheart.1998.274.4.h1386

[7] W.J. Bos. Reconstruction of brachial artery pressure from noninvasive finger pressure measurements., Circulation 1996; 94: 1870–1875.

DOI: 10.1161/01.cir.94.8.1870

[8] Swamy. G, Ling. Q, Li. T. Mukkamala, R. Blind identification of the central aortic pressure waveform from multiple peripheral arterial pressure waveforms. Conf Proc IEEE Eng Med Biol Sci1: 1822–1825, (2006).

DOI: 10.1109/iembs.2006.260538

[9] G. Swamy, Q. Ling, T. Li, and R. Mukkamala, Blind identification of the aortic pressure waveform from multiple peripheral artery pressure waveforms, Amer.J. Physiol, vol. 292, no. 5, p.2257–2264, (2007).

DOI: 10.1152/ajpheart.01159.2006

[10] K. Abed-Meraim, W. Qiu, and Y. Hua, Blind system identification, Proc. of IEEE, vol. 85, no. 12, pp.1310-1332, (1997).

DOI: 10.1109/5.622507

[11] H. Liu and G. Xu, A deterministic approach to blind symbol estimation, IEEE Signal Processing Lett, vol. 1, p.205–207, Dec. (1994).

DOI: 10.1109/97.338754