Stability Assessment of Minor-Caliber Vessel Perfusion System for Ex Vivo

Yan Qiu Liu; Nan Huang

doi:10.4028/www.scientific.net/AMM.631-632.594

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 631-632Stability Assessment of Minor-Caliber Vessel...

Stability Assessment of Minor-Caliber Vessel Perfusion System for Ex Vivo

Abstract:

Biggish animal models were applied in perfusion system for ex vivo research. But the disadvantages is the needs for more research funding and better surgical skills to perform which many researchers lack. A minor-caliber vessel perfusion system for ex vivo was designed and constructed to simulate pulsatile situation in vivo. The parameters mimicked the physiological measures of New Zealand rabbit. Pulse is 250 beats per minute. Diastolic blood pressure is 12.666KPa, and systolic blood pressure is 14.665KPa. The vessel perfusion system can regulate pulse pressure, the state of laminar flow, and shear stress. To culture several vessels simultaneously for control, the pressures data of 4 baths was analyzed with one way analysis of variance. The results show that the perfusion system is stable, and pressure difference of 4 baths is not significant.

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Periodical:

Applied Mechanics and Materials (Volumes 631-632)

Pages:

594-597

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.631-632.594

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Online since:

September 2014

Authors:

Yan Qiu Liu, Nan Huang

Keywords:

Analysis of Variance, Minor-Caliber Vessel Perfusion System, Pulsatile Culture, System Stability

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