Apple Snails Polysaccharide Extraction and Pharmacological Potential Study In Vitro

Jian Tao Liu; Zi Hao Deng; Jian Hua Huang; Ya Wang; Jun Chang; Du Zhu

doi:10.4028/www.scientific.net/AMM.651-653.207

Paper Titles

A Novel Deproteinized Bovine Bone Scaffold Containing Chitosan Microspheres for Controlled Delivery of BMP-2
p.187

A PVP-Based Quartz Crystal Microbalance Sensor for H₂S Detection
p.191

Analysis of the Factors in Affecting the Performance of Coal Liquefaction
p.195

Analysis of Trichome Density and the Content of Glandular Secretion on Different Flue-Cured Tobacco Leaves
p.200

Apple Snails Polysaccharide Extraction and Pharmacological Potential Study In Vitro
p.207

Application of Modified Chitosan in Fruit Juice Clarification
p.211

Biodegradation of Direct Red 28 and Direct Yellow 12 by a Novel Bacterial Consortium
p.215

Correlation between Anthocyanins, Total Phenolics Content and Antioxidant Activity of Purple Corn (Zea mays L.)
p.220

Effect of Endoplasmic Reticulum Stress on Resveratrol-Induced Cardioprotection
p.227

HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 651-653Apple Snails Polysaccharide Extraction and...

Apple Snails Polysaccharide Extraction and Pharmacological Potential Study In Vitro

Abstract:

Apple Snails is a snail-like animal. Being snail-like animals recognized as an edible aquatic animal and widely employed in traditional Chinese medicine, this study intends to reveal pharmacological potential of Apple Snails polysaccharide. Crude soluble polysaccharide of Apple Snails was first extracted using the hot water extraction and ethanol precipitation method. And the crude polysaccharide was purified successively using the Sevag method. After purification we found that and apple snails is rich in polysaccharide and the total polysaccharide content can reach to 68.4%. Using Fenton reactions, we found that antioxidant potential efficiency of apple snails polysaccharide is dose-dependent and can reach to 83.77% at the concentration of 5 mg/mL. Importantly, apple snails polysaccharide can efficiently inhibit lung cancer cell line A-549 proliferation in vitro and over 50% cell was killed in the dose of 200 mg/ml at 24 hours post treatment, implying that apple snails polysaccharide is a potential anti-tumor candidate.