Prophylactic Effect of Dragon-Pearl Tea on HCl/Ethanol Induced Gastric Injury in ICR Mice

Rui Wang; Xin Zhao

doi:10.4028/www.scientific.net/AMM.651-653.273

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 651-653Prophylactic Effect of Dragon-Pearl Tea on...

Prophylactic Effect of Dragon-Pearl Tea on HCl/Ethanol Induced Gastric Injury in ICR Mice

Abstract:

Dragon-pearl tea is a traditional Chinese drink consumed in Southwest of China. In the present study, the preventive effect of Dragon-pearl tea on gastric injury was determined in ICR mice. High concentrations of Dragon-pearl tea were observed to reduce the levels of the serum proinflammatory cytokines, IL-6 and TNF-α, compared with low concentrations of Dragon-pearl tea. Gastric secretion volumes were highest in control mice and reduced in 500, 1,000 and 1,500 mg/kg Dragon-pearl tea treated mice. The pH levels of gastric juice samples obtained from each group revealed the opposite correlation. Gastric injury levels in mice treated with Dragon-pearl tea were identified to be significantly reduced, demonstrating its anti-inflammatory properties. Administration of 1,500 mg Dragon-pearl tea (79.4%) by gavage was demonstrated to induce the highest inhibitory effect on gastric injury. Results of the current study indicate that Dragon-pearl tea exhibits marked preventive effects on gastric injury.

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Periodical:

Applied Mechanics and Materials (Volumes 651-653)

Pages:

273-276

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.651-653.273

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Online since:

September 2014

Authors:

Rui Wang, Xin Zhao*

Keywords:

Cytokine, Dragon-Pearl Tea, Gastric Injury, Gastric Secretion Volume, ICR Mice

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* - Corresponding Author

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