Synthesis and Blood Compatibility of Fluorinated Polyurethane Elastomer

Abstract:

In this paper, for the purpose of improving the hemocompatibility and surface tension of thermoplastic polyurethane (TPU) elastomers, poly butylene glycol ether hexafluoride fluoride ether glycol (PF) mixture with polytetramethylene ether glycol (PTMEG) was used as soft segments to synthesize a series of fluorinated thermoplastic polyurethane elastomers (FTPU) by two-step polymerization. The hemocompatibility in vitro was evaluated with platelet-rich plasma (PRP) contact tests. It was found that almost no platelet adhesion and activation was observed on the surface of FTPU elastomer when fluorine content was above 6wt% because of its low surface energy. The results indicated that fluorinated chain can be easily enriched on the surface of films because of higher C-F bond energy which due to greater micro-phase separation.

• Periodical: Applied Mechanics and Materials (Volume 685)
• Pages: 473-476
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.685.473
• Online since: October 2014
• Authors: Run Ping Jia*, An Xin Zong, Xin Yao He, Lu Wei
• Keywords: Blood Compatibility, Fluorinated Polyurethane, Synthesis

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