Orthogonal Analysis Methodology for the Extraction of Polysaccharides from the Root of Rhodiola sachalinensis A. BOR and Evaluation its Hypoglycemic Effects

Yan Liang; Feng Lin Li; Chuan Jun Zhang; Hui Yu

doi:10.4028/www.scientific.net/AMM.694.576

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Orthogonal Analysis Methodology for the Extraction of Polysaccharides from the Root of Rhodiola sachalinensis A. BOR and Evaluation its Hypoglycemic Effects

Abstract:

The present study was carried out to establish the optimum microwave-assisted extraction (MAE) conditions of polysaccharides from root of Rhodiola sachalinensis A. BOR (RSPs) by using o orthogonal analysis methodology. Moreover, the hypoglycemic effects of RSPs were investigated. The results indicated that the optimal extraction conditions of RSPs were liquid-solid ratio of 45:1 mL/g, irradiation power of 480 W, and irradiation time of 8 min. The animal experiment results demonstrated that RSPs could significantly increase body weights, serum insulin levels, and reduce fasting blood glucose (FBG) levels, which suggested that RSPs possesses hypoglycemic effects,.