Indirect Additive Manufacturing Processing of Poly-Lactide-co-Glycolide

Abstract:

The research and development of biomaterials have brought about new treatments in regenerative medicine. The research work presented in this paper focus on the use of Poly-Lactide-co-glycolide (PLGA) in the fabrication of patient specific fracture fixation plate by indirect additive manufacturing method. The use of biopolymers such as PLGA has been seen as a solution to the problems of stress shield and post-surgery inherent in biometal fixation plates. This paper discusses the consequence of this processing method on characteristics and properties of the PLGA. PLGA of ratio 50:50, 65:35 and 85:15 was processed and compared. The granules of PLGA were positioned in the cavity of the stereolithography (SLA) mould and heated under constant pressure with sintering temperature of 73°C for 2.0hours. Both the variation in samples fabricated from this process with the designed model and the changes in material characteristics are below 10%. The flexural strength for PLGA of ratio 50:50, 65:35 and 85:15 is 73.8±2.3MPa, 75.0±2.8, 60.0±11.7, respectively. The characteristics and mechanical tests indicate that the results were comparable with conventional processing of PLGA.

• Periodical: Applied Mechanics and Materials (Volumes 754-755)
• Pages: 985-989
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.754-755.985
• Online since: April 2015
• Authors: Shah Fenner Khan*, M.J. German, K.W. Dalgarno
• Keywords: Fixation Plates, Fracture, Indirect Additive Manufacturing, Poly-Lactide-co-Glycolide, Sintering

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