In view of the universal present situation where general rural buildings has low earthquake resistance ability, this paper, based on the base Isolation theory and the steel-asphalt isolation layer, proposes the steel-asphalt isolation pier to overcome the shortcomings of relatively complex construction and inconvenient volume production. The present study has also carried full-scale model experiment on the houses of single-layer full-scale masonry structure. The result shows that with the sine wave input of different acceleration amplitude, the superstructure acceleration weakens more than 40% and gets good damping effect because a majority of seismic energy has been absorbed by the isolation pier; and when the acceleration amplitude is below 0.30 grams, the steel of isolation pier is to be at the elastic state and can reset automatically after shock, which can satisfy the requirements of the seismic design. However, in order to meet the demand of the topic research, the present study has only done experiment on the small earthquake. According to the research findings, the attenuation coefficient , on the whole, tend to increase with the increase of acceleration peak value.