An experimental study was made of the mechanical properties of large scale confined concrete subjected to the axial compression test. Eleven tied concrete columns and six plain concrete prisms were tested. In the test, each specimen had the same transverse reinforcement configuration, and similar volumetric ratio of lateral steel, while different size. The test results in this paper indicate that the size of the specimen has no obvious relationship with the ultimate strength, however, it does affect the post-peak ductility to some extent. As a supplement to the experimental study, a finite element method was adopted to imitate the mechanical behavior of the confined concrete under axial compression. The results of the imitation in this paper indicate the confinement mechanism of large scale specimens.