Single-Photon Emission Computed Tomography with ¹⁹⁹Tl in Diagnostics of Malignant Tumors of the Larynx and Laryngopharynx

Abstract:

The purpose of research was to investigate the diagnostic capabilities of single-photon emission computed tomography (SPECT) with Thallium-199 in the diagnostics of malignant tumors of the larynx and laryngopharynx. The study included patients with primary and recurrent malignant tumors of the larynx or laryngopharynx, and patients with benign diseases of the larynx. All patients underwent SPECT of the larynx after intravenous administration of ¹⁹⁹Tl. It turned out that SPECT with ¹⁹⁹Tl is an effective method for diagnosing laryngeal and laryngopharyngeal cancer, having indices of sensitivity, specificity, and accuracy of 95%, 100% and 96.7% respectively. According to our data, in the visualization of regional metastases the sensitivity of SPECT with ¹⁹⁹Tl has amounted to 75%.

• Periodical: Advanced Materials Research (Volume 1084)
• Pages: 476-478
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1084.476
• Online since: January 2015
• Authors: Roman Zelchan*, Vladimir Chernov, Anna Titskaya, Ivan Sinilkin, Svetlana Chizhevskaya, Evgeniy Ts. Choynzonov
• Keywords: ¹⁹⁹Tl-Chloride, Laryngeal Cancer, Laryngopharyngeal Cancer, Single Photon Emission Computed Tomography (SPECT)

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