Basic Approach toward Sensor Searching for a Molecular Recognition Site of Electron Transfer Proteins
As a basic study to search a molecular recognition site in electron transfer proteins, optically-active ruthenium complexes, [RuII/III(bcmaa)(bpy)] (BCMAA: N,Nbis( carboxymethyl)amino acid, BPY: 2,2’-bipyridine), were designed and prepared. The electron transfer reaction with cytochrome c553 (Alcaligenes xylosoxidans GIFU1051) was kinetically investigated, and its enantio-selectivity was detected. Based on the results of enantio-selective behavior for cytochrome c553, the local structure of molecular recognition site of cytochrome c553 was discussed.
Masayuki Nogami, Riguang Jin, Toshihiro Kasuga and Wantai Yang
T. Kato et al., "Basic Approach toward Sensor Searching for a Molecular Recognition Site of Electron Transfer Proteins", Advanced Materials Research, Vols. 11-12, pp. 343-346, 2006