Inorganic-Organic Thin-Layers which Transform Bio-Molecule Binding into Visible Color Change

Abstract:

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SiO2 thin-films were prepared by thermal oxidation method. It showed uniform color based on the thin-film interference of visible light. Then we made biotin antenna on the top of SiO2 thin-film. Biotin is one of the vitamins and it has high association constant with protein avidin. After immersed the substrate into avidin solution, certain color changes based on the self-assembling of avidin on its surface were observed. By the immersing these substrates into mono-dispersed polystyrene particle solution, a polystyrene particle layer was formed onto avidin SAMs and it brought dynamic interference color change. As a result, this substrate could sense the avidin molecules over 1.0×10-8M of its concentration by naked eyes.

Info:

Periodical:

Advanced Materials Research (Volumes 11-12)

Main Theme:

Edited by:

Masayuki Nogami, Riguang Jin, Toshihiro Kasuga and Wantai Yang

Pages:

631-634

DOI:

10.4028/www.scientific.net/AMR.11-12.631

Citation:

R. Tominaga et al., "Inorganic-Organic Thin-Layers which Transform Bio-Molecule Binding into Visible Color Change", Advanced Materials Research, Vols. 11-12, pp. 631-634, 2006

Online since:

February 2006

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Price:

$35.00

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