Inorganic-Organic Thin-Layers which Transform Bio-Molecule Binding into Visible Color Change

R. Tominaga; M. Sivakumar; Masayoshi Tanaka; Takatoshi Kinoshita

doi:10.4028/www.scientific.net/AMR.11-12.631

Paper Titles

Sialite Technology
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Preparation and Characterization of RF/SiO₂ Hybrid Aerogel by Sol-Gel Method
p.619

Organization of Photosynthetic Antenna Complex in Lipid Bilayers
p.623

Preparation and Optical Characterization of Particle Multilayer with Coherent Structure
p.627

Inorganic-Organic Thin-Layers which Transform Bio-Molecule Binding into Visible Color Change
p.631

Construction of Self-Organized Interface via Monodisperse Block Copolypeptide Amphiphile
p.635

Kinetics of Supramolecular Polymerization: MSOA and HG Mechanisms
p.639

Synthesis of Amphiphilic Diblock Copolymer of Methoxy Poly(ethylene glycol)-b-polyester and Its Self-Assemble Behavior
p.643

Effect of Rolling Deformation on Microstructure of AZ31 Magnesium Alloy
p.649

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Inorganic-Organic Thin-Layers which Transform Bio-Molecule Binding into Visible Color Change

Abstract:

SiO2 thin-films were prepared by thermal oxidation method. It showed uniform color based on the thin-film interference of visible light. Then we made biotin antenna on the top of SiO2 thin-film. Biotin is one of the vitamins and it has high association constant with protein avidin. After immersed the substrate into avidin solution, certain color changes based on the self-assembling of avidin on its surface were observed. By the immersing these substrates into mono-dispersed polystyrene particle solution, a polystyrene particle layer was formed onto avidin SAMs and it brought dynamic interference color change. As a result, this substrate could sense the avidin molecules over 1.0×10-8M of its concentration by naked eyes.