Nanoemulsion: Formation, Characterization, Properties and Applications - A Review

Article Preview

Abstract:

In this paper, the formation, characterizaton, properties and applications of nanoemulsions are reviewed and summarized. Nanoemulsions are under extensive investigation as it can aid to recover the residual oil from reservoir rock in Oil Recovery application because of the submicron sized emulsion. Nanoemulsion is thermodynamically or kinetically stable system in which two or more immiscible phases that is made up at least one phase dispersed in others by mechanical shearing with appropriate surfactants. Nanoemulsions possess stability against creaming or sedimentation due to their small particle size while Ostwald ripening forming the main mechanism of nanoemulsion breakdown. Nanoemulsion has droplet sizes of the internal phase less than 500nm. Particle size and surface properties of droplets of nanoemulsion plays an important factor in the biological behavior of the formulation. Nanoemulsion shows great promise for the future of oil industries and biotechnologies, cosmetics and drug therapies.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

147-152

Citation:

Online since:

July 2015

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2015 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] L.D. Gaudio, R. Bortolo, and T.P. Lockhart, Nanoemulsions: A New Vehicle for Chemical Additive Delivery, , no. Spe 106016, (2007).

DOI: 10.2118/106016-ms

Google Scholar

[2] L. Mingliang, S. Houtai, J. Zilong, W. Qingzhi, and L. Lejun, Preparation and Performance of Environment friendly Nanoemulsion with Antiscaling, (2012).

Google Scholar

[3] K. P. Hoelscher, G. De Stefano, M. Riley, and S. Young, Application of Nanotechnology in Drilling Fluids, no. spe 157031, (2012).

DOI: 10.2118/157031-ms

Google Scholar

[4] D. S. Bernardi, T. a Pereira, N. R. Maciel, J. Bortoloto, G. S. Viera, G. C. Oliveira, and P. a Rocha-Filho, Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments., J. Nanobiotechnology, vol. 9, Jan. 2011, p.44.

DOI: 10.1186/1477-3155-9-44

Google Scholar

[5] S. Benita, and M. Y. Levy, Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization, Journal of pharmaceutical science, vol 82, (1993).

DOI: 10.1002/jps.2600821102

Google Scholar

[6] H. Nakajima, Industrial Applications of Microemulsions, Marcel Dekker: New York, Vol. 66, 1997, pp.175-197.

Google Scholar

[7] K. Bouchemal, S. Briançon, E. Perrier, and H. Fessi, Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation., Int. J. Pharm., vol. 280, no. 1–2, Aug. 2004, p.241–51.

DOI: 10.1016/j.ijpharm.2004.05.016

Google Scholar

[8] B. Abismail, J.P. Canseliar, A.M. Wilhelm, H. Delmas, C. Gourdon, Emulsification by Ultrasound: Drop Size Distribution and Stability, Ultrasonic Sonochemistry. 6, 1999, pp.75-83.

DOI: 10.1016/s1350-4177(98)00027-3

Google Scholar

[9] J. Eccleston, Microemulsions. In: Encyclopedia of Pharmaceutical Technology, Marcel Dekker, New York, Vol 9, 1994, pp.375-421.

Google Scholar

[10] P. Becher, Emulsions: Theory and Practice, Reinhold, New York, (1965).

Google Scholar

[11] D. Myers, Surfaces, Interfaces, and Colloids, Wiley, New York, (1999).

Google Scholar

[12] J.C. Johnson, Emulsifiers and Emulsifying Techniques, Noyes Data, Park Ridge, New Jersey, (1979).

Google Scholar

[13] K.K. Chong, G.G. Zhong, G.C. Han, S. Hee Jong, M.P. Kyung, J. Soo, Physicochemical characterization and evaluation of a micro emulsion system for oral delivery of cyclosporine A, Int J Pharm. 161, 1998, p.75–86.

Google Scholar

[14] M.J. Lawrence, D. Gareth, Micro emulsion-based media as novel drug delivery systems, Adv Drug Delivery Rev 45, 2000 , p.89–121.

DOI: 10.1016/s0169-409x(00)00103-4

Google Scholar

[15] C. Bilbao-Sainz, D.F. Wood, T.G. Williams, T.H. Mchugh, and R.D. Avena Bustillos Nanoemulsions prepared by a low-energy emulsification method applied to edible films, J. Agric. Food Chem vol 58, 2010, pp.11932-11938.

DOI: 10.1021/jf102341r

Google Scholar

[16] C. Solans, P. Izquierdo, J. Nolla, N. Azemar, Nanoemulsion, Curr Opin Colloid Interface Science, Vol 10, 2005, pp.102-112.

Google Scholar

[17] A. Mandal, A. Bera, K. Ojha, and T. Kumar, Characterization of Surfactant Stabilized Nanoemulsion and Its Use in Enhanced Oil Recovery, Society of Petroleum Engineers, (2012).

DOI: 10.2118/155406-ms

Google Scholar

[18] S. Debnath, Satayanarayana, and G.V. Kumar, Nanoemulsion- A Method to Improve the Solubility of Liphophilic Drug, An International Journal of Advances In Pharmaceutical Sciences, vol 2, 2011, pp.72-83.

Google Scholar

[19] S. Kentish, T.J. Wooster, M. Ashokkumar, S. Balachandran, R. Mawson, and L. Simons, The Use of Ultrasonics for Nanoemulsion Preparation, Journal of Innovative Food Science and Emerging Technologies, vol 9, pp.170-175, (2008).

DOI: 10.1016/j.ifset.2007.07.005

Google Scholar

[20] M.Y. Koroleve, and E.V. Yurtov, Nanoemulsions: the properties, methods of preparation and promising applications, Russian Chemical Review, vol 8, 2012, pp.21-43.

Google Scholar

[21] D. S. Bernardi, T. a Pereira, N. R. Maciel, J. Bortoloto, G. S. Viera, G. C. Oliveira, and P. a Rocha-Filho, Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments., J. Nanobiotechnology, vol. 9, Jan. 2011, p.44.

DOI: 10.1186/1477-3155-9-44

Google Scholar

[22] A. Chucheval, and, R.C.Y. Chow, A Study on Emulsification of Oil by Power Ultrasound, Journal of Ultrasonic Sonochemistry, vol 15, 2008, pp.916-920.

DOI: 10.1016/j.ultsonch.2008.02.004

Google Scholar

[23] D.M. Higgins, D.M. Skauen, Influence of Power on Quality of Emulsion Prepared by Ultrasound, J. Pharm. Sci, Vol 61(1), 1972, pp.1567-1570.

Google Scholar

[24] S. Muzudmar, P. Senthil Kumar, A.B. Pandit, Emulsification by Ultrasound: Relation Between Intensity and Emulsion Quality, Indian J. Chem. Technology, Vol 4, 1997, pp.277-284.

Google Scholar

[25] P. Shah and D. Bhalodia, Nanoemulsion a for various lipophilic drug diagnostic agents etc. pharmaceutical review, Sys Rev. Pharm, 2011, pp.24-31.

Google Scholar

[26] P. Bhatt and S. Madhav, A detailed review on nanoemulsion drug delivery system, International Journal Pharmacy Science and Research, 2011, pp.2292-2298.

Google Scholar

[27] N. Sharma, M. Bansal and S. Visht, Nanoemulsion: A new concept of delivery system, 2010, pp.2-6.

Google Scholar

[28] Qian Chang and D. Julian Mc Clements, Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: Factors affecting particle size, Elsevier B.V., vol 25, 2011, pp.1000-1008.

DOI: 10.1016/j.foodhyd.2010.09.017

Google Scholar

[29] G. Guglielmini, Nanostructured Novel Carrier for Topical Application, Clin Dermatol, Vol 26, 2008, pp.341-346.

Google Scholar

[30] S. Tamilvanan, Submicron Emulsions as a Carrier for Topical (Ocular and Percutaneous) and Nasal Drug Delivery, Indian J Pharm Educ, Vol. 38 (2), 2004, pp.73-78.

Google Scholar