Functionalized Antimicrobial Thin Films Based on Antibiotic Imbedded in Polymer Matrix for Implants Coating

Abstract:

In this study we investigated the possibility to use in implantology of a new composite made from antibiotic imbedded in polymer matrix with goal to merge the mechanical advantages of the metallic substrate with the excellent corrosion protection of the polymer and antimicrobial effect of the antibiotics. Furthermore the addition of small quantity of bioactive glass allows the antibiotic release and hastens the osteointegration. The biological properties of the coatings were tested including the microbial viability using Gram - and Gram + bacterial strains with known antibiotic susceptibility behavior. The proposed system could be used for development of new antimicrobial materials or strategies for fighting medical biofilm pathogens often implicated in the occurrence of chronic infections.

• Periodical: Advanced Materials Research (Volume 1128)
• Pages: 144-148
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1128.144
• Online since: October 2015
• Authors: Laura Floroian*, Mihaela Badea, Dan Floroian, Marius Moga, Cornel Samoila
• Keywords: Antimicrobial Effect, Biomedical Composites, Laser-Assisted Transfer

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