Due to the promising properties of high entropy alloy, TiVCrAlSi high entropy alloy coating was prepared on Ti-6Al-4V alloy surface by laser cladding. The microstructure and phase analysis of as-cast TiVCrAlSi alloy and laser clad coating were characterized by scanning electron microscope and X-ray diffraction. The results indicate that as-cast TiVCrAlSi alloy is mainly composed of (Ti,V)5Si3 and bcc phase. The laser clad coating is metallurgically bonded to the substrate with few pores and cracks. Laser clad TiVCrAlSi coating is also composed of (Ti,V)5Si3 and bcc phases.