Modification of Coconut-Shell Activated Carbon and its Controlled Release Property for Nicotinic Acid
In this paper, coconut-shell activated carbons (CSAC) used as the carrier of nicotinic acid (VPP) and the process of controlled release of VPP were studied. CSACs with relatively high yield and good adsorptive capacity prepared by CO2 activation method under the condition of 850oC, 1.5h activation time and 1.5L/min CO2 flow rate, were used as the VPP carrier. Langmuir model was suitable for describing the process of CSAC adsorbing VPP, and the maximum adsorptive capacity of CSAC was 136.32mg/g. The cumulative release percentages of VPP in distilled water, simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) were 22.53%, 45.86% and 53.94%, respectively. Higuchi model was the most suitable for describing the processes of CSAC releasing of VPP in the different media.
Guojun Zhang and Jessica Xu
W. Lu et al., "Modification of Coconut-Shell Activated Carbon and its Controlled Release Property for Nicotinic Acid", Advanced Materials Research, Vols. 160-162, pp. 1239-1244, 2011