Active Mass Damper has been proven to be efficient in suppressing structure vibration. Previous studies of AMD have been concentrated on the vibration control of buildings under earthquake excitation, whereas few investigation of wind-induced bridge vibration control has been conducted. In consideration of the characteristics of one suspension pipeline bridge which behaves dramatic lateral and torsional response under fluctuating wind action, a two-DOFs TMD/AMD system for suppressing both lateral and torsional responses was proposed. The bridge is modeled using Ansys and the buffeting responses of the bridge under TMD, AMD control are respectively simulated and analyzed by MATLAB/Simulink. The efficiency of different control system has been studied. The results show that two-DOFs AMD system has a better performance in suppressing the buffeting response of lateral bending and torsion. In addition, AMD system can be applicable to a wider range of frequency and therefore manifests the more stable performance than TMD under fluctuating wind loads which contain various frequency components.