Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y

Abstract:

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Potato virus Y (PVY) is one of the most important viruses that infect Solanaceous crops. In the study, the antigenic epitopes were predicted using computer-assisted analysis, and many potential regions of antigenic epitopes were located. Many properties of coat protein, such as the antigenic index, α-helix, β-sheet, β-turn, coil structure, hydrophilicity, surface probability, and flexibility, were analyzed with several algorithms in some softwares. Based on the rules for location the antigenic epitopes in the regions including β-turns and coil structures with the high hydrophilicity and surface probability, the predicted epitopes were located in the region of amino acid position 8-22, 24-38, 45-55, 240-255, respectively. It is helpful to prepare the antiserum of PVY based on the prediction result of antigenic epitope.

Info:

Periodical:

Advanced Materials Research (Volumes 183-185)

Edited by:

Yanguo Shi and Jinlong Zuo

Pages:

1204-1208

DOI:

10.4028/www.scientific.net/AMR.183-185.1204

Citation:

S. H. Guo et al., "Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y", Advanced Materials Research, Vols. 183-185, pp. 1204-1208, 2011

Online since:

January 2011

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Price:

$35.00

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