LiNi0.5Mn1.5O4 powders have been prepared by a solution combustion method at 300-800oC. X-ray diffraction (XRD) and scanning electric microscope (SEM) were used to determine the phase composition and micro morphology of the products. The results indicate that the products with single phase LiNi0.5Mn1.5O4 can be obtained at 400-600oC. The electrochemical performance was tested by a coin-type battery. The product prepared at 600oC has the best electrochemical performance. The maximum capacity of the product prepared at 600oC is 135mAh/g at the current density of 30mA/g, and after 30 cycles, the capacity fades little.