The POB/PTFE composites were prepared by blending-cold pressing-sintering-hot pressing method. Influence of POB content on mechanical and tribological properties of the composites was investigated. Worn surfaces were analyzed by scanning electron microscope (SEM). The results indicated that ball indentation hardness and compressive strength of POB/PTFE increase with increasing POB content in composites. Tensile strength, elongation and impact strength of POB/PTFE decrease with increasing POB content in composites. Friction coefficient of composites increases compared to PTFE. Wear resistance of POB/PTFE composites was improved with filling POB. The POB/PTFE composite incorporating 20% POB has best comprehensive mechanical properties. Wear mechanism of PTFE are abrasive wear. Wear mechanism of POB/PTFE composites mainly are fatigue wear and flaking.