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A Knitted Scaffold for Tendon Engineering Using Poly (Lactic Acid) Fibers

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Abstract:

A tubal knitted scaffold fabricated from poly(lactic acid) (PLA) yarns was given in this work. The performance of the scaffold during degradation in vitro and the morphology of the scaffold with cells (monkey dermal fibroblasts) were examined. The scaffold fabricated from poly(glycolic acid) (PGA) yarns was manufactured as the control. Results showed that the PLA scaffold could keep much more tensile strength during degradation in vitro, compared with the PGA scaffold. However, cell attachment and proliferation on the PGA scaffold were better than on the PLA scaffold.

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Info:

Periodical:

Advanced Materials Research (Volumes 197-198)

Pages:

164-167

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.197-198.164

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Online since:

February 2011

Authors:

Zheng Guo, Jin Jing Chen, Pei Hua Zhang

Keywords:

Degradation, PGA, Poly(lactic acid) (PLA), Scaffold, Tendon, Tissue Engineering

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© 2011 Trans Tech Publications Ltd. All Rights Reserved

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