Biomechanical Numerical Simulation of Bone Tissue Engineering Scaffolds
Biomechanical compatibility is one of the key targets for bone tissue engineering scaffolds. As the repair of hard tissue, the scaffold should be of similar strength and elasticity modulus with replaced bone to avoid stress shielding. This paper combines the finite element method and the computer simulation technology analyzing the stress influence of the porous β-TCP scaffold and the middle of femur in different internal architectures, and the simulation results show that scaffold implants at lower porosity conducive to the elimination of stress shielding. The aim of this paper is to provide the theory and design basis on the bone tissue engineering scaffolds.
L. L. Lin et al., "Biomechanical Numerical Simulation of Bone Tissue Engineering Scaffolds", Advanced Materials Research, Vol. 213, pp. 306-310, 2011