Computer-Aided Design and Fabrication of Bio-Mimetic Materials and Scaffold Micro-Structures

Abstract:

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Computer-aided design (CAD) has proven effective in enabling novel approaches for tissue engineering applications. This paper demonstrates the applicability of various mathematical methods to design and fabricate bio-mimetic materials via two illustrative examples. Firstly, CAD models of cellular biomaterials that mimic the micro-structure of cuttlefish bone are designed based on the principles of the homogenization method. Secondly, a three-dimensional bi-objective topology optimization approach based upon the inverse homogenization method is used to design scaffold micro-structures with tailored effective stiffness and permeability properties. Consequently, solid free-form fabrication is used to fabricate such cellular bio-mimetic materials, which show a great potential in tissue engineering applications.

Info:

Periodical:

Edited by:

Zhang Yushu

Pages:

628-632

DOI:

10.4028/www.scientific.net/AMR.213.628

Citation:

Y. H. Chen et al., "Computer-Aided Design and Fabrication of Bio-Mimetic Materials and Scaffold Micro-Structures", Advanced Materials Research, Vol. 213, pp. 628-632, 2011

Online since:

February 2011

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Price:

$35.00

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