Determination of Ascorbic Acid Based on Gold Nanoparticles-L-Alanine/GCE

Article Preview

Abstract:

A Gold nanoparticles-L-alanine modified glass electrode has been successfully fabricated by using layer-by-layer self-assembly technology and used for determination of ascorbic acid. First, the clean electrode was immersed into L-Alanine solution to acquire a L-Alanine film on the surface of GCE and dried at room temperature, then the gold colloid was dipped onto the L-Alanine film. The electrochemical behaviors of ascorbic acid at the modified electrode were investigated by cyclic voltammetry and current-time techniques. The results showed that the sensor produced high sensitivity and good stability to ascorbic acid and the current was linear with the concentration of ascorbic acid in the range of 1.20×10-5 to 1.60×10-4 mol/L with a detection limit of 1.00×10-5 mol/L.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

498-502

Citation:

Online since:

February 2011

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2011 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] H.R. Zare,N. Rajabzadeh, N. Nasirizadeh, M.M. Ardakani,J. Simultaneous determination of dopamine, ascorbic acid and uric acid with electrospun carbon nanofibers modified electrode[J]. Electroanal. Chem. 2006, 589: 60-64.

DOI: 10.1016/j.jelechem.2006.01.011

Google Scholar

[2] J.A. Driko,J. Chapman V.J. Hunter. The natural history of chronic allograft nephropathy[J]. Am. Coll. Nure. 2003, 22: 118-122.

Google Scholar

[3] H. Puzanowska-Tarasiewicz, M. Tarasiewicz, N. Omieljaniuk. Titrimetric determination of ascorbic acid with bromate using perphenazine as redox indicator[J]. Fresenius Z. Anal. Chem. 1980, 303: 412.

DOI: 10.1007/bf00470005

Google Scholar

[4] N. Saari,A. Osman, J. Selamat, et al. Ascorbate oxidase from starfruit(Averrhoa carambola): preparation and its application in the determination of ascorbic acid from fruit juices[J]. Food Chem. 1999, 66: 57-60.

DOI: 10.1016/s0308-8146(98)00170-8

Google Scholar

[5] J.B. Raoof, R. Ojani, A. Kiani. Carbon paste electrode spiked with ferrocene carboxylic acid and its application to the electrocatalytic determination of ascorbic acid[J]. Electroanal. Chem. 2001, 515: 45-48.

DOI: 10.1016/s0022-0728(01)00642-8

Google Scholar

[6] Gema Cabello-Carramolino, Maria Dolores Petit-Dominguez. Development of new sol-gel carbon composite electrodes and their application as electrochemical sensors[J]. Microchim Acta. 2009, 164: 405-410.

DOI: 10.1007/s00604-008-0074-6

Google Scholar

[7] Guangfeng Wang, Jingao Sun, Wei Zhang, et al. Simultaneous determination of dopamine, uric acid and ascorbic acid with LaFeO3 nanoparticles modified electrode[J]. Microchim Acta. 2009, 164: 357-362.

DOI: 10.1007/s00604-008-0066-6

Google Scholar

[8] D. Hemandez-Santos M.B. Gonzalez-Garcla A.C. Garcla. Simultaneous determination of ascorbic acid, dopamine and uric acid at Pt nanoparticles decorated multiwall carbon nanotubes modified GCE[J]. Electroanalysis, 2002, 14: 1225-1228.

DOI: 10.1002/elan.200900525

Google Scholar

[9] E. Katz,I. Willner,J. Wang. Catalytic oxidation of ascorbic acid on 2D and 3D monolayers of 4-hydroxythiophenol[J]. Electroanal. Chem. 2004, 16: 19-23.

Google Scholar

[10] Lin li, Cou peihong. The preparation and application of electrochemical sensor on Nano silver colloid labeled DNA[J]. Journal of Wenzhou Medical College. 2008. 3(2): 170-171.

Google Scholar

[11] Wang Y H, Gu H Y. Hemoglobin co-immobilized with silver–silver oxide nanoparticles on a bare silver electrode for hydrogen peroxide electroanalysis[J]. Microchimica. Acta., 2009, 17: 68-72.

DOI: 10.1007/s00604-008-0029-y

Google Scholar

[12] Ann N.Y. Clark, L.C. Electrode systems for continuous in cardiovascular surgery [J]. Acad. Sci. 1962, 102 (2): 29-45.

Google Scholar

[13] Jana NR, Murphy CJ. Seeding growth for size control of 5-40 nm diameter gold nanoparticles[J]. Langmuir, 2001, 17: 6782.

DOI: 10.1021/la0104323

Google Scholar