Using the static and dynamic triaxial experimental machine, experimental study of the strength of wet-screened aggregate concrete are carried out under biaxial compression stress ratios, 0.25, 0.5, 0.75 and 1 after 0, 50, 100, 150, 200, 250, 300 cycles of freeze-thaw. The change of surface of wet-screened aggregate concrete specimens after different cycles of freeze-thaw are observed and described. The failure characteristic of specimens and the direction of the cracks are also observed. Based on the test data, the influence of freeze-thaw cycles and compressive stress ratio on the ultimate compressive strength and corresponding stress-strain relationship is analyzed respectively. The relationships between the ultimate compressive strength and freeze-thaw cycles, the stress ratios are given, respectively. On this basis, the unified failure criterion with consideration of the influence of freeze-thaw cycles and stress ratio is proposed. It can serve as a reference for the maintenance, design and the life prediction of ocean structures, hydraulic structures, marine structures and offshore platform in cold regions.