Based on the theory of sensitivity analysis, the local/global sensitivity analysis of parameters for the modeling of thermal transport in aquifer under special groundwater flow and heat source conditions were carried out with the summer running of Groundwater Source Heat Pump (GSHP) system as a study case, by taking the temperature of typical observation points and thermal affected zone (TAZ) of injecting water at the end of summer as the model outputs. The results showed that the sensitivity of each modeling output was various for the different parameter in local analysis. The orders of local sensitivity coefficients of the nine parameters for two modeling outputs were almost coincident. In global sensitivity analysis, the sensitivity of the parameter being investigated was influenced by the different values of other parameters. The two modeling outputs almost had the same variation tendency of global sensitivity with different parameter combinations.