Antimicrobial Resistance Surveillance of Klebsiella Spp. Isolated from the First Bethune Hospital

Article Preview

Abstract:

Klebsiella spp. are opportunistic pathogens which frequently cause community and nosocomial infections. The present study aimed to evaluate the antibiotic resistance profiles of Klebsiella spp. isolated from the First Bethune Hospital. Disk diffusion method was used to study the antimicrobial resistance. The data were analyzed by WHONET 5 software according to Clinical and Laboratory Standards Institute (CLSI). The majority of 3149 strains of Klebsiella spp. were collected from sputum(1890, 60.0%),blood(378, 12.0%) and secretions(315, 10.0%). The percentage of extended-spectrum β-lactamases (ESBLs) in Klebsiella spp. was 53.8% (1694/3149). Klebsiella spp. strains were frequently resistant to multiple antibiotics. Antimicrobial resistance of ESBL-producing Klebsiella spp. was more serious than that of non-ESBL-producing isolates. The results suggest that surveillance of antimicrobial resistance in Klebsiella spp. is necessary.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 268-270)

Pages:

1954-1956

Citation:

Online since:

July 2011

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2011 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] H. Knothe, P. Shah, V. Krcmery, M. Antal and S. Mitsuhashi: Infection Vol. 11 (1983), No. 6, pp.315-317.

Google Scholar

[2] PA. Bradford: Clin Microbiol Rev Vol. 14 (2001), No. 4, pp.933-951.

Google Scholar

[3] P. Lal, A. Kapil, BK. Das and S. Sood: Indian J Med Rev, Vol. 125 (2007), No. 2, pp.173-178.

Google Scholar

[4] R. Misra, M. Kumar, PK. Menon and VC. Ohri: Indian J Pathol Microbiol Vol. 44 (2001), No. 4, pp.427-429.

Google Scholar

[5] K. Lim, C. Yeo, R. Yasin, S. Puthucheary and KL. Thong: J Med Microbiol Vol. 58 (2009), No. 11, pp.1463-1469.

Google Scholar

[6] J. Bell , M. Chitsaz, J. Turnidge, M. Barton, LJ. Walters and RN. Jones: J Clin Microbiol Vol. 45 (2007), No. 5, pp.1478-1482.

Google Scholar

[7] P. Hsueh, R. Badal, S. Hawser, DJ. Hoban, SK. Bouchillon, Y. Ni, DL. Paterson and 2008 Asia–Pacific SMART Group: Int J Antimicrob Agents Vol. 36 (2010), No. 5, pp.408-414.

DOI: 10.1016/j.ijantimicag.2010.07.002

Google Scholar

[8] J. Yoo, J. Byeon, J Yang, JI Yoo, GT. Chung and YS. Lee: Diagn Microbiol Infect Dis Vol. 67 (2010), No. 3, pp.261-265.

Google Scholar

[9] Y. Chong, H. Yakushiji, Y. Ito and T. Kamimura: Eur J Clin Microbiol Infect Dis, Vol. 30 (2011), No. 1, pp.83-87.

Google Scholar

[10] R. Cantón, A. Novais, A. Valverde, E. Machado, L. Peixe, F. Baquero and TM. Coque: Clin Microbiol Infect Vol. 14 (2008), No. Suppl 1, pp.144-153.

DOI: 10.1111/j.1469-0691.2007.01850.x

Google Scholar