Correlation between Clinicopathology and Immunolocalization of Heat Shock Protein 72 and Glycoprotein 96 in Human Hepatocellular Carcinomas

Xiao Ping Wang; Huan Ping Lin; Qiao Xia Wang

doi:10.4028/www.scientific.net/AMR.282-283.3

Paper Titles

Correlation between Clinicopathology and Immunolocalization of Heat Shock Protein 72 and Glycoprotein 96 in Human Hepatocellular Carcinomas
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 282-283Correlation between Clinicopathology and...

Correlation between Clinicopathology and Immunolocalization of Heat Shock Protein 72 and Glycoprotein 96 in Human Hepatocellular Carcinomas

Abstract:

Heat shock protein 72 (HSP72) and glycoprotein 96 (gp96) are highly expressed in cancer tissues. Recent studies indicate the possible roles of HSP72 and gp96 in the development and progression of gastrointestinal carcinomas but detailed information is still ambiguous. The aim of the study is to investigate the correlation between clinicopathology and immunolocalization of HSP72 and gp96 in human hepatocellular carcinoma. Immunohistochemistry demonstrated that HSP72 and gp96 expression in hepatocellular carcinomas with metastasis was significantly higher than those with non-metastasis. HSP72 and gp96 expression were significantly associated with the presence of tumor infiltration, lymph node and remote metastasis.

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Advanced Materials Research (Volumes 282-283)

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3-6

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https://doi.org/10.4028/www.scientific.net/AMR.282-283.3

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July 2011

Authors:

Xiao Ping Wang, Huan Ping Lin, Qiao Xia Wang

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Clinicopathology, Glycoprotein 96 (GP96), Heat Shock Protein 72 (HSP72), Hepatocellular Carcinoma, Prognosis

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