Gas-Electrospun Degradable PEG/PBT-HA: Potential Scaffold for Tissue Engineering
In this work, the composite nanofibers of polybutylene terephthalate/polyethylene glycol (PEG/PBT) with difference intrinsic viscosity and different ratio of the hard-segment to the soft-segment were obtained by gas-electrospun. The PEG/PBT-HA composite nanofibers were also obtained by gas-electrospun. PEG/PBT and PEG/PBT-HA composite nanofibers were characterized using scanning electron microscopy (SEM), horizontal attenuated total reflectance for Fourier transformation infra-red spectrometer (HATR-FTIR), dynamic contact angle measurement and differential scanning calorimetry (DSC). The results strongly suggest that this synthetic matrix combines with the advantages of synthetic biodegradable polymers, nanometer-scale dimension mimicking the natural ECM, may represent an ideal tissue engineering scaffold, especially for soft tissue, such as skin and cartilage tissue engineering scaffold.
Xiaoming Sang, Pengcheng Wang, Liqun Ai, Yungang Li and Jinglong Bu
X. Z. Yang et al., "Gas-Electrospun Degradable PEG/PBT-HA: Potential Scaffold for Tissue Engineering", Advanced Materials Research, Vols. 284-286, pp. 923-927, 2011