Gas-Electrospun Degradable PEG/PBT-HA: Potential Scaffold for Tissue Engineering

Abstract:

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In this work, the composite nanofibers of polybutylene terephthalate/polyethylene glycol (PEG/PBT) with difference intrinsic viscosity and different ratio of the hard-segment to the soft-segment were obtained by gas-electrospun. The PEG/PBT-HA composite nanofibers were also obtained by gas-electrospun. PEG/PBT and PEG/PBT-HA composite nanofibers were characterized using scanning electron microscopy (SEM), horizontal attenuated total reflectance for Fourier transformation infra-red spectrometer (HATR-FTIR), dynamic contact angle measurement and differential scanning calorimetry (DSC). The results strongly suggest that this synthetic matrix combines with the advantages of synthetic biodegradable polymers, nanometer-scale dimension mimicking the natural ECM, may represent an ideal tissue engineering scaffold, especially for soft tissue, such as skin and cartilage tissue engineering scaffold.

Info:

Periodical:

Advanced Materials Research (Volumes 284-286)

Main Theme:

Edited by:

Xiaoming Sang, Pengcheng Wang, Liqun Ai, Yungang Li and Jinglong Bu

Pages:

923-927

DOI:

10.4028/www.scientific.net/AMR.284-286.923

Citation:

X. Z. Yang et al., "Gas-Electrospun Degradable PEG/PBT-HA: Potential Scaffold for Tissue Engineering", Advanced Materials Research, Vols. 284-286, pp. 923-927, 2011

Online since:

July 2011

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$35.00

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