Al-matrix self-lubricating which added MoS2 as solid lubricant was prepared by casting under variation in content of Si、Fe、Mn、MoS2、Cr3C2. Friction and wear behavior were investigated on MPX-2000 friction and abrasion machine. The microscopic structure and phases were analyzed by metallographic microscopic and XRD. The results show that the main factor influencing friction coefficient is Si, it can reduce the wear rate. Addition of MoS2 can reduce friction coefficient, Fe is used to improve the mechanical properties. Cr3C2 enhances the wear resistance.