Process Optimization of Cefradine/ Montmorillionite in Solution Intercalation

Yan Zhao  Zhao; Wen Ji  Guo; Lan  Wang

doi:10.4028/www.scientific.net/AMR.306-307.831

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Process Optimization of Cefradine/ Montmorillionite in Solution Intercalation
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 306-307Process Optimization of Cefradine/...

Process Optimization of Cefradine/ Montmorillionite in Solution Intercalation

Abstract:

One-factor-at-a-time design and orthogonal design were used in the experimental design to optimize the process of preparation for Cefradine /Montmorillionite composites in solution intercalation. Experimental results indicate that drug initial concentration was the most significant condition for optimal preparation of composites, intercalation time and reaction temperature were not so significant. In our paper, the maximum drug load occurred at reaction temperature of 60°C with the intercalation time of 2h when the drug concentration (mass ratio of cefradine to MMT) was 2:1.

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Periodical:

Advanced Materials Research (Volumes 306-307)

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831-834

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https://doi.org/10.4028/www.scientific.net/AMR.306-307.831

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August 2011

Authors:

Yan Zhao Zhao, Wen Ji Guo, Lan Wang

Keywords:

Cefradine, Montmorillionite, Orthogonal Designing, Solution Intercalation

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