Research on the Modification of Poly(L-Lactic Acid) by Glucose via Direct Melt Polycondensation

Abstract:

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Directly using L-lactic acid (L-LA) and glucose (Glu) as the starting materials, novel biodegradable material poly(L-lactic acid-co-glucose) [P(L-LA-co-Glu)] was synthesized via direct melt polycondensation. The copolymers P(L-LA-co-Glu)s at different molar feed ratios were characterized by FTIR, 1H-NMR, GPC, DSC and XRD. All poly(L-lactic acid) modified by Glu was partly crystalline. And their Mw, Tm, and crystallinity basically increased with the increase of the molar feed ratio n(L-LA) : n(Glu). When n(Glu) : n(L-LA) was 1 : 750, the biggest Mw was 5900 Da, and all Mw could meet the requirement for drug delivery application.

Info:

Periodical:

Advanced Materials Research (Volumes 311-313)

Edited by:

Zhongning Guo

Pages:

1106-1109

DOI:

10.4028/www.scientific.net/AMR.311-313.1106

Citation:

S. H. Luo et al., "Research on the Modification of Poly(L-Lactic Acid) by Glucose via Direct Melt Polycondensation", Advanced Materials Research, Vols. 311-313, pp. 1106-1109, 2011

Online since:

August 2011

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Price:

$35.00

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