Molybdenum coatings are commonly used in the industry for protection against wear. With an aim to investigate the erosion properties of this coating, molybdenum coating was sprayed onto both AISI 1045 and nickel-based superalloy (GH3039) substrate by electro-thermal explosion ultra-high speed spraying process. Phase composition, microstructure and microhardness of the coatings were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and microhardness tester, respectively. Erosion tests of the coating at different particle impingement angel and material sample temperature were performed on a GW/CS-MS type tester. The high erosion resistance of the coating can mainly be attributed to high hardness, low porosity and metallurgical bonding between the coating and the substrate.