Synthesis of some Curcumin Analogues under Ultrasound Irradiation

Abstract:

A convenient method to synthesize curcumin and its five analogues, which were named as 1,7-diphenyl-1,6-heptadiene-3,5-dione,1,7-Bis-(4-hydroxy-phenyl)-1,6-heptadiene-3,5-dione,1,7-Bis-(4-methoxy-phenyl)-1,6-heptadiene-3,5-dione,1,7-Bis-(2-hydroxy-3-methoxy-phenyl)-1,6-heptadiene-3,5-dione and 1,7-Bis-(2,3-dimethoxy-phenyl)-1,6-heptadiene-3,5-dione respectively, via the Claisen condensation of aromatic aldehyde and 2,4-pentanedione in the presence of trimethyl borate and monoethanolamine under ultrasound irradition was reported. The corresponding physical properties were characterized by IR, 1HNMR spectra and elemental analysis studies.

• Periodical: Advanced Materials Research (Volumes 332-334)
• Pages: 1623-1626
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.332-334.1623
• Online since: September 2011
• Authors: Ying Jie Lei, Ye Bi, Ou Yang Jie
• Keywords: Curcumin Analogues, Synthesis, Ultrasound irradiation

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