Preparation and Chiral Resolution Properties of L-Phenylalanine Modified Poly(NIPAAm-Co-AAc) Hydrogels
Poly(NIPAAm-co-AAc) hydrogels of different ratios were prepared by copolymerization and then modified with L-phenylalanine by amidation of carboxyl groups of acrylic acid. The structures of the hydrogels were identified by IR and the chiral separation experiments of hydrogels on D/L-phenylalanine were investigated. The results showed that the chiral hydrogels exhibited enantioselectivity for L-phenylalanine and the resolution capability increased with the rising of temperature and contents of L-phenylalanine groups.
Xiaoming Qian and Huawu Liu
D. D. Zhang et al., "Preparation and Chiral Resolution Properties of L-Phenylalanine Modified Poly(NIPAAm-Co-AAc) Hydrogels", Advanced Materials Research, Vols. 332-334, pp. 1852-1855, 2011