This paper introduces the design of small jacquard plain weave imitating silk shirt fabric aiming at the characteristic of the pearl fiber. Pearl fiber and plush cotton fiber are chosen and blended. It’s weaving process is presented. The producing techniques were researched according to the characteristics of the fibers and yarns. A series of technology measures in process of producing were taken. So the weaving efficiency reaches 92%, and the finished woven fabric is artistic, moisture absorpting, smooth, cool and comfortable. It has a comparatively high strength, perfect elasticity and durable shape.