PVC coated fabric has poor self-cleaning property. The surface treatment with TiO2 can improve the self-cleaning property of PVC coated fabric by photocatalysis. The surface treatment agent used in this experiment contains nano TiO2 power and PVDF. The treatment of coupling agent can improve the surface properties of nano TiO2 power and the performance of the surface treatment agent. The effects of coupling agent on the modification of nano TiO2 power and the surface morphology of the treated PVC coated fabric were researched by IR and SEM respectively. The photocatalysis of the top layer on the treated PVC coated fabric was evaluated by the degradation of methyl orange dye.