Salt slurry is the solid waste of the salt industry. The study object is the salt slurry in Jianghan Salt & Chemical Complex. This study investigates the application of the salt slurry in high density polymer saturated brine-based drilling fluid. This laboratory study indicates that the salt slurry may improve the rheology behavior of the drilling fluid, and may measure up both the API and the HTHP filtrate loss. On the premise of the same density and pH value as the basic drilling fluid recipe, with the increasing of the salt slurry, the YP/PV value increased, but the friction coefficient of the mud-cake increased. This investigate will reduce the cost of the high density polymer saturated brine-based drilling fluid with the salt slurry as a resource, and will have important significance for both recycling economy and the cleaner production of the salt industry.