Study on Dynamic Characteristics of the Hippocampal Neuron under Current Stimulation
The hippocampal CA1 pyramid neuron has plenty of discharge actions. In the thesis, the dynamic characteristics of the hippocampal neuron model are analyzed and discussed by the neurodynamic theory and methods. Under the current stimulation, the hippocampal CA1 pyramid neuron has plenty of discharge patterns, and can generate many discharge patterns such as period, the chaos, and so on. Under the stimulation current amplitude unchanging, the dynamic characteristics of the hippocampal neuron have something to do with not only the current’s stimulation amplitude, but also the stimulation time’s length, which isn’t the same with common neurons such as the Hindmarsh-Rose neuron. When the stimulation amplitude increases gradually or the stimulation time prolongs, The neuron model’s ISI gradually drops off, whose changing trend approximates to an exponential function, that is to say, the discharge frequency gets quicker and quicker. In addition, the hippocampal CA1 pyramid neuron model has class II neural excitability. This investigation is helpful to know and investigate deeply the dynamic characteristics and the bifurcation mechanism of the hippocampal neuron; and it provides a certain theory assist to investigate the neural diseases such as the Alzheimer disease by neurodynamics.
Y. P. Peng "Study on Dynamic Characteristics of the Hippocampal Neuron under Current Stimulation", Advanced Materials Research, Vols. 341-342, pp. 350-354, 2012