Mixing efficiency is an important parameter in the design of many industrial processes in stirred tanks. In this study, CFD technology was used to simulate the mixing process inside the stirred tank with dislocated blades and standard turbine. Calculations were performed to study the effects of agitator speed and the configuration of impellers on mixing efficiency. The results showed that the flow field in the stirred tank with the dislocated blades is better than the standard turbine, and the flow number of the dislocated blades had been improved while the power number had been reduced. According to calculation results of Wr, we found the mixing efficiency of the dislocated blades had been improved about 4 times than that of standard turbine.