A new RC frame multi-ribbed composite walls structure is provided by using low yield strength steel. Two calculating structures are analyzed which one is the RC frame shear wall structure used as a comparison, and the other is the RC frame multi-ribbed composite walls structure. The nonlinear earthquake responses of the structures are calculated by using program IDARC2D.The nonlinear dynamic analysis models of the structures are established with retrogressive three-linear resilience model for beam, column and RC shear wall elements, while a smooth hysteretic model is proposed for representing low yield strength steel panels. The nonlinear dynamic time-history analysis of the structures under horizontal earthquake waves has been carried out. The earthquake responses of the structures and energy dissipation are studied, which provide more data information for the comprehension of earthquake responses and seismic performance of the RC frame multi-ribbed composite walls structure. The calculating results show that the low yield strength steel panels have obvious seismic mitigation effects, and that RC frame multi-ribbed composite walls structure has good seismic capacity.