Considering the erosion effect of underground water deteriorate the micro structure of rock which results in the time effect of rock deform, the paper developed a uniaxial compression equipment for rock creep under chemical and stress coupling action. It adopts good corrosion prevention design, can conveniently test the rock uniaxial compression creep effect with erosion. Take limestone as study object, the paper carried out uniaxial compression creep tests with different PH environment. Compared the results of different tests and found that limestone has obvious creep effect in acid solution, the smaller the PH value is, the greater the creep deform is. For the same test specimen, the creep deform of primary stage is larger than that of later stage. In each level load, the creep velocity decreases along with the time increasing. Analyzed result shows that the equipment has provided basement for studying the rock creep mechanism with chemistry and stress interaction.