Kinetics of SiO2 Nanofibres Dissolution in the Simulated Lung Environment

Lukáš Brázda; Jarmila Studničková; Petr Exnar; Aleš Helebrant

doi:10.4028/www.scientific.net/AMR.39-40.347

Paper Titles

Mechanism of Generation of Tableware Surface Defects during Dishwashing Process
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Biomedical Thermodynamics and Implantology Aspects of Biocompatible Glass-Ceramics and Otherwise Modified Inorganic Materials and Surfaces
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Phospho-Silicate Glasses, Self-Degradable in Environment Conditions
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Continuous Measurement of the Dissolution Rate of Ions from Glasses
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Kinetics of SiO₂ Nanofibres Dissolution in the Simulated Lung Environment
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Glass Surface Analysis by an Optimized Sequential Chemical Etching Technique Using the Corrosive Agent HF/HNO₃
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Kinetics of E-glass Fibres Leaching in Borate Solution and Distilled Water
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Ageing of Clay-Based Materials
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Chemical Durability of Glass Thermal Insulation Fibers in Borate and Phosphate Water Solutions
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 39-40Kinetics of SiO2 Nanofibres Dissolution in the...

Kinetics of SiO₂ Nanofibres Dissolution in the Simulated Lung Environment

Abstract:

To avoid the risk of cancer or respiratory diseases, nanofibres have to biodegrade in lung fluid when inhaled. There are two main factors affecting behaviour of the nanofibres in living tissue – geometry of fibres and biopersistence. A dissolution rate of SiO2 nanofibres in a simulated lung environment was tested in this work. Distilled water buffered with TRIS and HCl to pH 7.6 was used as a simple simulated extracellular lung fluid (SLF). Fibres were tested both under the static and dynamic conditions of the corrosive solution. Dissolution rates were calculated from both SiO2 concentration changes in solutions and weight changes of fibres during the exposition. The dissolution rate of tested SiO2 nanofibres was at the rate limit, where fibres could be considered as harmless for health.