The Study on the Antioxidative Activity of Resveratrol in Senescence-Accelerated Mouse Prone/8 (SAMP8)

Abstract:

In the present study, we examined resveratrol(RES)extracted from Polygonum cuspidatum on antioxidative effects in the senescence-accelerated mouse (SAM). We fed resveratrol to young adult SAM mice at doses of 25,50,100mg/(kg•bw) in their standard powder diet for 8-week. The body weight, organ weights and oxidation products of malondialdehyde (MDA) in the liver of the SAM were determined. The results showed that the SAM mice were no dose-related change in either body weight or organ weights, the amount of MDA declined distinctly in the mouse liver. In conclusion, resveratrol may have an antioxidant effect.

• Periodical: Advanced Materials Research (Volumes 396-398)
• Pages: 1398-1401
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.396-398.1398
• Online since: November 2011
• Authors: Gui Shan Liu, Ze Sheng Zhang, Bo Yang, Wei He
• Keywords: (E)-Resveratrol, Antioxidative Effects, Body Weight, Malondialdehyde (MDA), Organ Weights

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