Investigation of Mass Sensitivity for the Piezoelectric Diaphragm Biosensor

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Abstract:

The mass sensitivity of a piezoelectric diaphragm biosensor has been investigated. The piezoelectric diaphragm utilizing a flexural vibration mode is an acoustic wave device which can be immobilized with a bio-molecular recognition layer on its surface. The mass sensitivity of the sensor was analyzed by the approximately theoretical and FEM methods, respectively. The sensitivity formula expressed by the structural parameters and the material parameter was educed for easy computing. The procedure utilizing Rayleigh method for the analytic solution of the sensitivity was introduced. The expression was verified by using a commercial FEM software package, ANSYS. The simulations are well consistent with the theory.

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245-249

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November 2011

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[1] T.M.H. Lee, Over-the-counter biosensors: Past, present, and future, Sensors, 8 (2008), 5535-5559.

DOI: 10.3390/s8095535

Google Scholar

[2] S. Song, H. Xu and C.H. Fan, Potential diagnostic applications of biosensors: current and future directions, International Journal of Nanomedicine, 1 (2006), 433-440.

DOI: 10.2147/nano.2006.1.4.433

Google Scholar

[3] J.J. Gooding, Biosensor technology for detecting biological warfare agents: Recent progress and future trends, Anal Chim Acta, 559 (2006), 137-151.

DOI: 10.1016/j.aca.2005.12.020

Google Scholar

[4] S. Li, W. Ren, X. Lu, Z. Xu, Z. Cheng, X. Chen, P. Shi, X. Wu and X. Yao, Ferroelectric Thin Film Diaphragm Resonators for Bio-Detection, Ferroelectrics, 410 (2011), 145-151.

DOI: 10.1080/00150193.2010.492743

Google Scholar

[5] S.W. Wenzel and R.M. White, ANALYTIC COMPARISON OF THE SENSITIVITIES OF BULK-WAVE, SURFACE-WAVE, AND FLEXURAL PLATE-WAVE ULTRASONIC GRAVIMETRIC SENSORS, Applied Physics Letters, 54 (1989), 1976-1978.

DOI: 10.1063/1.101189

Google Scholar